MAP3K8 antibody (pThr290)

Catalog No. ABIN7299172

The Rabbit Polyclonal anti-MAP3K8 antibody (ABIN7299172) specifically detects MAP3K8 in WB, IHC and IF. The antibody is reactive with Human, Rat, Mouse, Cow and Monkey samples.

Quick Overview for MAP3K8 antibody (pThr290) (ABIN7299172)

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Reactivity: Human, Rat, Mouse, Cow, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MAP3K8 Antibody

Binding Specificity: pThr290

Purpose: Rabbit polyclonal antibody to TPL2 (Phospho-T290)

Specificity: Recognizes endogenous levels of TPL2 protein only when phosphorylated at T290.

Characteristics: Rabbit polyclonal antibody to TPL2 (pT290)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding T290 of human TPL2 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MAP3K8

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Alternative Name: TPL2

Background: COT, ESTF, Mitogen-activated protein kinase kinase kinase 8, Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2, TPL-2

Gene ID: 1326, 26410, 116596

UniProt: P41279

Pathways: PI3K-Akt Signaling, TCR Signaling