GRIN1/NMDAR1 antibody

Catalog No. ABIN272046

The Rabbit Polyclonal anti-GRIN1/NMDAR1 antibody (ABIN272046) specifically detects GRIN1/NMDAR1 in WB, IF, IHC (p) and EIA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GRIN1/NMDAR1 antibody (ABIN272046)

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN1/NMDAR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-GRIN1/NMDAR1 Antibody

Specificity: This antibody detects endogenous levels of NMDAR1 protein.

Purification: Affinity-Chromatography using epitope-specific immunogen

Application Details

Application Notes: ELISA: 1: 5000approx. 1: 10000. IF: 1: 50approx. 1: 200. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GRIN1/NMDAR1

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Alternative Name: NMDA Receptor 1

Background: NMDA receptor subtypes of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. NMDAR1 plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission and is involved in the cell surface targeting of NMDA receptors.Synonyms: GRIN1, Glutamate [NMDA] receptor subunit zeta-1, NMDAR1

Molecular Weight: approx. 130 kDa

Gene ID: 2902

NCBI Accession: NP_000823

UniProt: Q05586

Pathways: Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity