GADD34 antibody

Catalog No. ABIN2721547

This Mouse Monoclonal antibody specifically detects GADD34 in WB, IHC, FACS and IF. It exhibits reactivity toward Human, Mouse, Rat, Monkey and Dog.

Quick Overview for GADD34 antibody (ABIN2721547)

Target: GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))

Reactivity: Human, Mouse, Rat, Monkey, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This GADD34 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 3D12

Product Details anti-GADD34 Antibody

Characteristics: Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 15A (PPP1R15A)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PPP1R15A(NP_055145) produced in HEK293T cell.

Isotype: IgG2b

Application Details

Application Notes: WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for GADD34

Target: GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))

Alternative Name: PPP1R15A

Background: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

Molecular Weight: 73.3 kDa

Gene ID: 23645

NCBI Accession: NM_014330

HGNC: 23645

Pathways: ER-Nucleus Signaling, Unfolded Protein Response