PDX1 antibody

Catalog No. ABIN2723507

This Mouse Monoclonal antibody specifically detects PDX1 in WB, IHC and IF. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for PDX1 antibody (ABIN2723507)

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 2A12

Product Details anti-PDX1 Antibody

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.

Isotype: IgG1

Application Details

Application Notes: WB 1:20000, IHC 1:50, IF 1:50~100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-PDX1 antibody (ABIN2723507)

Pondugala, Sasikala, Guduru, Rebala, Nageshwar Reddy: "Interferon-? Decreases Nuclear Localization of Pdx-1 and Triggers ?-Cell Dysfunction in Chronic Pancreatitis." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 35, Issue 7, pp. 523-9, (2015) (PubMed).

Target Details for PDX1

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Alternative Name: PDX1

Molecular Weight: 30.6 kDa

Gene ID: 3651

NCBI Accession: NM_000209

HGNC: 3651

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location