Notch1 antibody (AA 2300-2556)

Catalog No. ABIN2727478

Cited in 1 publication. The Mouse Monoclonal anti-Notch1 antibody (Clone 3E12) (ABIN2727478) specifically detects Notch1 in WB, IHC, IF and RPPA. The antibody is reactive with Human samples.

Quick Overview for Notch1 antibody (AA 2300-2556) (ABIN2727478)

Target: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Notch1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Reverse Phase Protein Array (RPPA)

Clone: 3E12

Product Details anti-Notch1 Antibody

Binding Specificity: AA 2300-2556

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Recombinant protein expressed in E.coli corresponding to amino acids 2300-2556 of human NOTCH1

Isotype: IgG2b

Application Details

Application Notes: WB: 1:1000, IHC 1,50, RPPA 1:75, IF: 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-Notch1 antibody (ABIN2727478)

Harada, Sato, Ikeda, Hsu, Igarashi, Nakanuma: "Notch1-Hes1 signalling axis in the tumourigenesis of biliary neuroendocrine tumours." in: Journal of clinical pathology, Vol. 66, Issue 5, pp. 386-91, (2013) (PubMed).

Target Details for Notch1

Target: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Alternative Name: Notch1

Molecular Weight: 270.6 kDa

Gene ID: 4851

NCBI Accession: NM_017617

HGNC: 4851

Pathways: Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development