SOD1 antibody

Catalog No. ABIN2732993

Cited in 2+ publications. The Mouse Monoclonal anti-SOD1 antibody (Clone 8B10) (ABIN2732993) specifically detects SOD1 in WB, IHC and FACS. The antibody is reactive with Human samples.

Quick Overview for SOD1 antibody (ABIN2732993)

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 8B10

Product Details anti-SOD1 Antibody

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human SOD1 (NP_000445) produced in HEK293T cell.

Isotype: IgG2b

Application Details

Application Notes: WB 1:1000~2000, IHC 1:50, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-SOD1 antibody (ABIN2732993)

Milillo, Molinario, Costanzi, Vischini, La Carpia, La Greca, Rigante, Gambaro, Gurrieri, Sangiorgi: "Defective activation of the MAPK/ERK pathway, leading to PARP1 and DNMT1 dysregulation, is a common defect in IgA nephropathy and Henoch-Schönlein purpura." in: Journal of nephrology, Vol. 31, Issue 5, pp. 731-741, (2018) (PubMed).

Benlloch, Obrador, Valles, Rodriguez, Sirerol, Alcácer, Pellicer, Salvador, Cerdá, Sáez, Estrela: "Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism." in: Antioxidants & redox signaling, Vol. 24, Issue 17, pp. 974-90, (2016) (PubMed).

Target Details for SOD1

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Alternative Name: SOD1

Molecular Weight: 15.8 kDa

Gene ID: 6647

NCBI Accession: NM_000454

HGNC: 6647

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis