STS antibody (N-Term) (Atto 647N)

Catalog No. ABIN2745511

Product Details anti-STS Antibody (Atto 647N)

Target: STS (Steroid Sulfatase (STS))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is conjugated to Atto 647N

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Specificity: Recognizes human and mouse Asc.

Cross-Reactivity: Human, Mouse (Murine)

Immunogen: Synthetic peptide corresponding to aa at the N-terminal human Asc.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: +4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.

Expiry Date: 12 months

Target Details for STS

Target: STS (Steroid Sulfatase (STS))

Alternative Name: Asc (STS Products)

Synonyms: 9130417A21Rik antibody, Asc antibody, CARD5 antibody, TMS-1 antibody, TNS1 antibody, masc antibody, ARSC antibody, ARSC1 antibody, ASC antibody, ES antibody, SSDD antibody, XLI antibody, PYD and CARD domain containing antibody, steroid sulfatase antibody, Pycard antibody, STS antibody, Sts antibody

Background: Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases.

UniProt: Q9ULZ3

Pathways: Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation