STS antibody (N-Term)

Catalog No. ABIN2745512

This Rabbit Polyclonal antibody specifically detects STS in WB, IHC, FACS, IF, ICC, IP and Func. It exhibits reactivity toward Human and Mouse.

Quick Overview for STS antibody (N-Term) (ABIN2745512)

Target: STS (Steroid Sulfatase (STS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Functional Studies (Func)

Product Details anti-STS Antibody

Binding Specificity: N-Term

Purpose: anti-Asc, pAb (AL177) (preservative free)

Specificity: Recognizes human and mouse Asc.

Characteristics: Polyclonal Antibody. Recognizes human and mouse Asc. Source: Rabbit. Applications: FUNC, ICC, IHC, IP, WB. Liquid. In PBS containing 10 % glycerol. Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases.

Immunogen: Synthetic peptide corresponding to aa at the N-terminal human Asc.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for STS

Target: STS (Steroid Sulfatase (STS))

Alternative Name: Asc

Background:

Alternate Names/Synonyms: Pycard, Target of Methylation-induced Silencing 1, TMS1, Caspase Recruitment Domain-containing Protein 5, Apoptosis-associated Speck-like Protein Containing CARD, CARD5

Product Description: Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases.

UniProt: Q9ULZ3

Pathways: Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation