H1 Histone Family, Member N, Testis-Specific (H1FNT) (C-Term) antibody

Catalog No. ABIN2774219

The Rabbit Polyclonal anti-H1 Histone Family, Member N, Testis-Specific antibody (ABIN2774219) specifically detects H1 Histone Family, Member N, Testis-Specific in WB. The antibody is reactive with Human samples.

Quick Overview for H1 Histone Family, Member N, Testis-Specific (H1FNT) (C-Term) antibody (ABIN2774219)

Target: H1 Histone Family, Member N, Testis-Specific (H1FNT)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Purpose: H1FNT Antibody - C-terminal region

Sequence: AKEEAGATAA DEGRGQAVKE DTTPRSGKDK RRSSKPREEK QEPKKPAQRT

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against H1FNT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human H1FNT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58274-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: H1 Histone Family, Member N, Testis-Specific (H1FNT)

Alternative Name: H1FNT

Background:

Background Information: H1FNT is essential for normal spermatogenesis and male fertility. It is required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. It is involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. H1FNT binds both double-stranded and single-stranded DNA, ATP and protamine-1.

Gene Name: H1 histone family, member N, testis-specific

Alternative Symbols: H1.7, H1T2, H1FNT

Protein Name: Testis-specific H1 histone

Molecular Weight: 27kDa

Gene ID: 341567

NCBI Accession: NP_861453

UniProt: Q75WM6