H1 Histone Family, Member N, Testis-Specific (H1FNT) (AA 35-130) antibody

Catalog No. ABIN7995910

The Rabbit Polyclonal anti-H1 Histone Family, Member N, Testis-Specific antibody is suitable to detect H1 Histone Family, Member N, Testis-Specific in samples from Human, Mouse and Rat. It has been validated for WB, FACS and ELISA.

Quick Overview for H1 Histone Family, Member N, Testis-Specific (H1FNT) (AA 35-130) antibody (ABIN7995910)

Target: H1 Histone Family, Member N, Testis-Specific (H1FNT)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Grade: Carrier-free

Product Details

Binding Specificity: AA 35-130

Purpose: Anti-H1-7 Antibody

Predicted Reactivity: Human H1-7 shares 61.3%,64.9 amino acid (aa) sequence identity with mouse,rat H1-7,respectively.

Characteristics: Anti-H1-7 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human H1-7 recombinant protein (Position: H35-R130). Human H1-7 shares 61.3% and 64.9 amino acid (aa) sequence identity with mouse and rat H1-7, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: H1 Histone Family, Member N, Testis-Specific (H1FNT)

Alternative Name: H1-7

Background:

Background: H1 histone family, member N, testis-specific is a member of the histone family of nuclear proteins which are a component of chromatin. In humans, this protein is encoded by the H1FNT gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. The related mouse gene encodes a testis specific protein that is required for spermatogenesis and male fertility.

Gene Full Name: H1.7 linker histone

Molecular Weight: 28 kDa

Gene ID: 341567

UniProt: Q75WM6