H1 Histone Family, Member N, Testis-Specific (H1FNT) antibody

Catalog No. ABIN7466629

The Rabbit Polyclonal anti-H1 Histone Family, Member N, Testis-Specific antibody is suitable to detect H1 Histone Family, Member N, Testis-Specific in samples from Human. It has been validated for WB.

Quick Overview for H1 Histone Family, Member N, Testis-Specific (H1FNT) antibody (ABIN7466629)

Target: H1 Histone Family, Member N, Testis-Specific (H1FNT)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Testis-specific H1 histone. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: MCF-7

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details

Target: H1 Histone Family, Member N, Testis-Specific (H1FNT)

Alternative Name: H1 histone family member N, testis specific

Background: H1 histone family member N, testis specific , H1.7 , H1T2,Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1.

Molecular Weight: 28 kDa

Gene ID: 341567

UniProt: Q75WM6