FGF8 antibody (C-Term)
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- Target See all FGF8 Antibodies
- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Guinea Pig, Pig, Zebrafish (Danio rerio), Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FGF8 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EGWYMAFTRK GRPRKGSKTR QHQREVHFMK RLPRGHHTTE QSLRFEFLNY
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 75%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 75%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against FGF8. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product FGF8 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 215 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
- Alternative Name
- FGF8 (FGF8 Products)
- Synonyms
- Aigf antibody, Fgf-8 antibody, AIGF antibody, FGF-8 antibody, HBGF-8 antibody, HH6 antibody, KAL6 antibody, fibroblast growth factor 8 antibody, Fgf8 antibody, FGF8 antibody
- Background
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The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
Alias Symbols: AIGF, HBGF-8, KAL6, MGC149376, FGF-8
Protein Interaction Partner: FGFR2, FGFR1, FGFR4, FGFR3, AR,
Protein Size: 215 - Molecular Weight
- 22 kDa
- Gene ID
- 2253
- NCBI Accession
- NM_006119, NP_006110
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis
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