EIF2AK2 antibody (Middle Region)
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- Target See all EIF2AK2 Antibodies
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Dog, Rabbit, Horse, Pig, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EIF2AK2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QVFKAKHRID GKTYVIKRVK YNNEKAEREV KALAKLDHVN IVHYNGCWDG
- Predicted Reactivity
- Cow: 92%, Dog: 83%, Horse: 91%, Human: 100%, Mouse: 83%, Pig: 83%, Rabbit: 100%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against EIF2AK2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human EIF2AK2
- Top Product
- Discover our top product EIF2AK2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 551 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
- Alternative Name
- EIF2AK2 (EIF2AK2 Products)
- Synonyms
- PKR antibody, pkr antibody, EIF2AK2 antibody, DKFZp469K1934 antibody, EIF2AK1 antibody, PRKR antibody, 2310047A08Rik antibody, 4732414G15Rik antibody, AI467567 antibody, AI747578 antibody, Pkr antibody, Prkr antibody, Tik antibody, eukaryotic translation initiation factor 2 alpha kinase 2 antibody, eukaryotic translation initiation factor 2-alpha kinase 2 antibody, EIF2AK2 antibody, eif2ak2 antibody, Eif2ak2 antibody
- Background
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EIF2AK2 might play a role in ER stress-induced apoptosis and in Alzheimer's disease. Alzheimer cases show prominent EIF2AK2 activation in association with neuritic plaques and pyramidal neurons in the hippocampus and neocortex.
Alias Symbols: EIF2AK1, MGC126524, PKR, PRKR
Protein Interaction Partner: UBC, TRAF6, TRAF5, TRAF2, EGFR, DHX9, STAU2, PRKRA, EIF2AK2, HECW2, TOP1, STAU1, DICER1, DHX30, EBNA1BP2, IGF2BP2, IGF2BP3, PABPC4, MOV10, ILF3, ILF2, HSP90AA1, EIF2A, NOC3L, GNL3, NOP2, HNRNPC, HIST1H1C, ELAVL1, NPM1, IL7R, gag, Jak2, TYK2, JAK1, EIF2S1,
Protein Size: 551 - Molecular Weight
- 62 kDa
- Gene ID
- 5610
- NCBI Accession
- NM_002759, NP_002750
- UniProt
- P19525
- Pathways
- DNA Damage Repair, ER-Nucleus Signaling, Hepatitis C
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