DNA2 antibody (Middle Region)

Catalog No. ABIN2774822

The Rabbit Polyclonal anti-DNA2 antibody (ABIN2774822) specifically detects DNA2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit samples.

Quick Overview for DNA2 antibody (Middle Region) (ABIN2774822)

Target: DNA2 (DNA Replication Helicase 2 Homolog (DNA2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DNA2 Antibody

Binding Specificity: Middle Region

Sequence: KLELEFYADY SDNPWLMGVF EPNNPVCFLN TDKVPAPEQV EKGGVSNVTE

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 85%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against DNA2L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DNA2L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 494 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DNA2

Target: DNA2 (DNA Replication Helicase 2 Homolog (DNA2))

Alternative Name: DNA2L

Background: DNA2L belongs to the DNA2/NAM7 helicase family. It may function in chromosomal DNA replication.
Alias Symbols: DNA2L, FLJ10063, KIAA0083, MGC133297
Protein Interaction Partner: FAM96B, CIAO1, UPF1, RPA3, RPA2, RPA1, LYN, MMS19, UBC,
Protein Size: 494

Molecular Weight: 54 kDa

Gene ID: 1763

NCBI Accession: NM_001080449

UniProt: P51530

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA