DNA2 antibody (Middle Region)

Catalog No. ABIN2774822

This anti-DNA2 antibody is a Rabbit Polyclonal antibody detecting DNA2 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit.

Quick Overview for DNA2 antibody (Middle Region) (ABIN2774822)

Target: DNA2 (DNA Replication Helicase 2 Homolog (DNA2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DNA2 Antibody

Binding Specificity: Middle Region

Sequence: KLELEFYADY SDNPWLMGVF EPNNPVCFLN TDKVPAPEQV EKGGVSNVTE

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 85%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against DNA2L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DNA2L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 494 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DNA2

Target: DNA2 (DNA Replication Helicase 2 Homolog (DNA2))

Alternative Name: DNA2L

Background: DNA2L belongs to the DNA2/NAM7 helicase family. It may function in chromosomal DNA replication.
Alias Symbols: DNA2L, FLJ10063, KIAA0083, MGC133297
Protein Interaction Partner: FAM96B, CIAO1, UPF1, RPA3, RPA2, RPA1, LYN, MMS19, UBC,
Protein Size: 494

Molecular Weight: 54 kDa

Gene ID: 1763

NCBI Accession: NM_001080449

UniProt: P51530

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA