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DDX21 antibody (C-Term)

DDX21 Reactivity: Human, Rat, Horse, Dog, Pig, Guinea Pig, Cow, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775198
  • Target See all DDX21 Antibodies
    DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
    Binding Specificity
    • 9
    • 8
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 38
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Horse, Dog, Pig, Guinea Pig, Cow, Rabbit
    Host
    • 38
    Rabbit
    Clonality
    • 37
    • 1
    Polyclonal
    Conjugate
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DDX21 antibody is un-conjugated
    Application
    • 27
    • 14
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    FRGQRDGNRR FRGQREGSRG PRGQRSGGGN KSNRSQNKGQ KRSFSKAFGQ
    Predicted Reactivity
    Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against DDX21. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human DDX21
    Top Product
    Discover our top product DDX21 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 783 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Miyazawa, Yoshikawa, Magae, Ishikawa, Izumikawa, Terukina, Suzuki, Nakamura-Fujiyama, Miura, Hayano, Komatsu, Isobe, Takahashi: "Human cell growth regulator Ly-1 antibody reactive homologue accelerates processing of preribosomal RNA." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 19, Issue 4, pp. 273-86, (2014) (PubMed).

    Romanova, Grand, Zhang, Rayner, Katoku-Kikyo, Kellner, Kikyo: "Critical role of nucleostemin in pre-rRNA processing." in: The Journal of biological chemistry, Vol. 284, Issue 8, pp. 4968-77, (2009) (PubMed).

  • Target
    DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
    Alternative Name
    DDX21 (DDX21 Products)
    Synonyms
    MGC130693 antibody, DDX21 antibody, cb960 antibody, wu:fi30c07 antibody, wu:fi34d08 antibody, GUA antibody, GURDB antibody, RH-II/GU antibody, RH-II/GuA antibody, Ddx21a antibody, AI255159 antibody, AL022742 antibody, D10Ertd645e antibody, D10Wsu42e antibody, DEAD-box helicase 21 L homeolog antibody, DExD-box helicase 21 antibody, DEAD-box helicase 21 antibody, DEAD (Asp-Glu-Ala-Asp) box helicase 21 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 antibody, ddx21.L antibody, DDX21 antibody, ddx21 antibody, Ddx21 antibody
    Background
    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX21 encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
    Alias Symbols: GUA, GURDB, RH-II/GU, RH-II/GuA
    Protein Interaction Partner: HUWE1, PA2G4, KPNA3, CEP250, SUMO2, SUMO3, STAU1, IVNS1ABP, UBC, MDM2, LGR4, SUMO1, ERG, WWOX, EED, rev, SRPK2, SRPK3, FBXO6, TARDBP, LYN, AICDA, PAN2, vif, WHSC1, VCAM1, ITGA4, IL7R, FN1, CSNK2A1, YWHAE, SMURF1, H2AFX, APTX, ESR1, FTSJ3, PCDHA2, RRP7A, R
    Protein Size: 783
    Molecular Weight
    86 kDa
    Gene ID
    9188
    NCBI Accession
    NM_004728, NP_004719
    UniProt
    Q9NR30
    Pathways
    SARS-CoV-2 Protein Interactome
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