IGFALS antibody (Middle Region)

Catalog No. ABIN2775292

Product Details anti-IGFALS Antibody

Target: IGFALS (Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFALS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PGLLGLRVLR LSHNAIASLR PRTFKDLHFL EELQLGHNRI RQLAERSFEG

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against IGFALS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IGFALS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 605 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IGFALS

Target: IGFALS (Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS))

Alternative Name: IGFALS (IGFALS Products)

Synonyms: ALS antibody, Albs antibody, mKIAA4111 antibody, Als antibody, insulin like growth factor binding protein acid labile subunit antibody, insulin like growth factor binding protein acid labile subunit L homeolog antibody, insulin-like growth factor binding protein, acid labile subunit antibody, IGFALS antibody, igfals.L antibody, Igfals antibody

Background: IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in IGFALS are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.
Alias Symbols: ALS
Protein Interaction Partner: PDCD6, IGF1, IGFBP5, IGFBP3,
Protein Size: 605

Molecular Weight: 63 kDa

Gene ID: 3483

NCBI Accession: NM_004970, NP_004961

UniProt: P35858