CRNN antibody (Middle Region)

Catalog No. ABIN2775428

The Rabbit Polyclonal anti-CRNN antibody is suitable to detect CRNN in samples from Human, Dog and Horse. It has been validated for WB.

Quick Overview for CRNN antibody (Middle Region) (ABIN2775428)

Target: CRNN (Cornulin (CRNN))

Reactivity: Human, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRNN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRNN Antibody

Binding Specificity: Middle Region

Purpose: CRNN Antibody - middle region

Sequence: GDRQPTVVGE EWVDDHSRET VILRLDQGNL HTSVSSAQGQ DAAQSEEKRG

Predicted Reactivity: Dog: 85%, Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CRNN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CRNN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42460-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRNN

Target: CRNN (Cornulin (CRNN))

Alternative Name: CRNN

Background:

Background Information: This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation.

Gene Name: Cornulin

Alternative Symbols: DRC1, PDRC1, SEP53, C1orf10

Protein Name: Cornulin

Molecular Weight: 54 kDa

Gene ID: 49860

NCBI Accession: NP_057274

UniProt: Q9UBG3