In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA1 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.
Alias Symbols: BSAS, HOX1, HOX1F
Protein Interaction Partner: KRTAP26-1, NOTCH2NL, KRTAP12-4, KRTAP10-3, KRTAP10-8, KRTAP4-11, KRTAP10-5, KRTAP10-11, KRTAP10-1, KRTAP10-9, TBC1D10C, KRTAP12-1, KRTAP12-2, LCE3E, LCE1B, TRIM42, LCE4A, MGAT5B, KRT40, KRTAP4-2, KRTAP4-7, KRTAP9-4, KRTAP9-2, KRTAP3-2, KRTAP4-12, CCDC33,
Protein Size: 132