GABRA2 antibody (C-Term)

Catalog No. ABIN2776108

The Rabbit Polyclonal anti-GABRA2 antibody is suitable to detect GABRA2 in samples from Human, Rat, Mouse, Dog, Cow, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for GABRA2 antibody (C-Term) (ABIN2776108)

Target: GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABRA2 Antibody

Binding Specificity: C-Term

Purpose: GABRA2 Antibody - C-terminal region

Sequence: RLNQYDLLGQ SIGKETIKSS TGEYTVMTAH FHLKRKIGYF VIQTYLPCIM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GABRA2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human GABRA2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34979-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABRA2

Target: GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))

Alternative Name: GABRA2

Background:

Background Information: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: gamma-aminobutyric acid type A receptor alpha2 subunit

Alternative Symbols: DEE78, EIEE78

Protein Name: gamma-aminobutyric acid receptor subunit alpha-2

Molecular Weight: 40kDa

Gene ID: 2555

NCBI Accession: NP_000798

UniProt: P47869