Serotonin Receptor 3A antibody (Middle Region)

Catalog No. ABIN2776369

This anti-Serotonin Receptor 3A antibody is a Rabbit Polyclonal antibody detecting Serotonin Receptor 3A in WB. Suitable for Human, Rat, Mouse, Dog, Cow, Horse, Guinea Pig, Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Serotonin Receptor 3A antibody (Middle Region) (ABIN2776369)

Target: Serotonin Receptor 3A (HTR3A)

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Guinea Pig, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 3A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Serotonin Receptor 3A Antibody

Binding Specificity: Middle Region

Sequence: PATAIGTPLI GVYFVVCMAL LVISLAETIF IVQLVHKQDL QRPVPDWLRH

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against Htr3a. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 483 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Alternative Name: Htr3a

Background: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Alias Symbols: 5-HT3, 5-HT3A, 5HT3, Htr3
Protein Size: 483

Molecular Weight: 55 kDa

Gene ID: 79246

NCBI Accession: NM_024394, NP_077370

UniProt: P35563

Pathways: Synaptic Membrane