KCTD11 antibody (N-Term)

Catalog No. ABIN2776370

This anti-KCTD11 antibody is a Rabbit Polyclonal antibody detecting KCTD11 in WB. Suitable for Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit and Goat.

Quick Overview for KCTD11 antibody (N-Term) (ABIN2776370)

Target: KCTD11 (Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCTD11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCTD11 Antibody

Binding Specificity: N-Term

Sequence: RLGRLDLPRG YGETALLRAE ADFYQIRPLL DALRELEASQ GTPAPTAALL

Predicted Reactivity: Cow: 100%, Goat: 90%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KCTD11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCTD11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 232 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCTD11

Target: KCTD11 (Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))

Alternative Name: KCTD11

Background: The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling. Its inactivation might lead to a deregulation of the tumor-promoting Hedgehog pathway in medulloblastoma.
Alias Symbols: C17orf36, MGC129844, REN, REN/KCTD11, KCASH1
Protein Interaction Partner: KCTD11, CUL3, HDAC1,
Protein Size: 232

Molecular Weight: 26 kDa

Gene ID: 147040

NCBI Accession: NM_001002914, NP_001002914

UniProt: Q693B1

Pathways: Hedgehog Signaling