PIAS2 antibody (C-Term)

Catalog No. ABIN2776423

This anti-PIAS2 antibody is a Rabbit Polyclonal antibody detecting PIAS2 in WB. Suitable for Human, Mouse, Dog, Cow, Horse and Rabbit.

Quick Overview for PIAS2 antibody (C-Term) (ABIN2776423)

Target: PIAS2 (Protein Inhibitor of Activated STAT, 2 (PIAS2))

Reactivity: Human, Mouse, Dog, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIAS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIAS2 Antibody

Binding Specificity: C-Term

Sequence: FLDSLTSPLT ASSTSVTTTS SHESSTHVSS SSSRSETGVI TSSGSNIPDI

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%

Characteristics: This is a rabbit polyclonal antibody against PIAS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PIAS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 621 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIAS2

Target: PIAS2 (Protein Inhibitor of Activated STAT, 2 (PIAS2))

Alternative Name: PIAS2

Background: PIAS2 may function as a co-repressor of Stat4.
Alias Symbols: DIP, MIZ, MIZ1, SIZ2, ARIP3, PIASX, ZMIZ4, PIASX-BETA, PIASX-ALPHA
Protein Interaction Partner: HIC1, GOLGA2, GFAP, PHC1, TRIM23, ZBTB8A, SUMO1P1, ACY3, TSR2, NAV2, CCHCR1, CCNDBP1, MAPKAPK2, ZBED1, PIAS2, SUMO1, UBE2I, TP53, PRKAB2, MX2, TRIM63, TRIM55, CTBP1, GTF2I, SUMO2, SUMO3, MYC, DNMT3A, TICAM2, RUFY1, PIAS4, C1QA, ADA, PAXIP1, UBC, PLAGL1, P
Protein Size: 621

Molecular Weight: 68 kDa

Gene ID: 9063

NCBI Accession: NM_004671, NP_004662

UniProt: O75928

Pathways: JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling