FZD2 antibody (N-Term)

Catalog No. ABIN502077

Cited in 1 publication. The Rabbit Polyclonal anti-FZD2 antibody (ABIN502077) specifically detects FZD2 in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Dog and Horse samples.

Quick Overview for FZD2 antibody (N-Term) (ABIN502077)

Target: FZD2 (Frizzled Family Receptor 2 (FZD2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FZD2 Antibody

Binding Specificity: N-Term

Purpose: FZD2 Antibody - N-terminal region

Sequence: MRPRSALPRL LLPLLLLPAA GPAQFHGEKG ISIPDHGFCQ PISIPLCTDI

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FZD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FZD2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41236-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-FZD2 antibody (ABIN502077)

Li, Chen, Hu, Xing, Sasaki, Villosis, Li, Nishita, Minami, Minoo: "Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2." in: BMC molecular biology, Vol. 9, pp. 11, (2008) (PubMed).

Target Details for FZD2

Target: FZD2 (Frizzled Family Receptor 2 (FZD2))

Alternative Name: FZD2

Background:

Background Information: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The expression of the FZD2 gene appears to be developmentally regulated, with high levels of expression in fetal kidney and lung an

Gene Name: Frizzled family receptor 2

Alternative Symbols: Fz2, fz-2, fzE2, hFz2, OMOD2

Protein Name: Frizzled-2

Molecular Weight: 63kDa

Gene ID: 2535

NCBI Accession: NP_001457

UniProt: Q14332

Pathways: WNT Signaling