WNT16 antibody (C-Term)

Catalog No. ABIN2776717

Product Details anti-WNT16 Antibody

Target: WNT16 (Wingless-Type MMTV Integration Site Family, Member 16 (WNT16))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT16 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: REKDQRKIPI HKDDLLYVNK SPNYCVEDKK LGIPGTQGRE CNRTSEGADG

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against WNT16. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WNT16

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 365 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WNT16

Target: WNT16 (Wingless-Type MMTV Integration Site Family, Member 16 (WNT16))

Alternative Name: WNT16 (WNT16 Products)

Synonyms: zgc:77293 antibody, E130309I19Rik antibody, Wnt family member 16 antibody, wingless-type MMTV integration site family, member 16 antibody, WNT16 antibody, wnt16 antibody, Wnt16 antibody

Background: WNT proteins are secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT16 contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen.
Alias Symbols: -
Protein Interaction Partner: BCL6,
Protein Size: 365

Molecular Weight: 38 kDa

Gene ID: 51384

NCBI Accession: NM_057168, NP_476509

UniProt: Q9UBV4

Pathways: WNT Signaling