MSH5 antibody (N-Term)

Catalog No. ABIN2776764

This Rabbit Polyclonal antibody specifically detects MSH5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig and Rabbit.

Quick Overview for MSH5 antibody (N-Term) (ABIN2776764)

Target: MSH5 (MutS Homolog 5 (MSH5))

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSH5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MSH5 Antibody

Binding Specificity: N-Term

Sequence: DENMTRFLGK LASQEHREPK RPEIIFLPSV DFGLEISKQR LLSGNYSFIP

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MSH5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MSH5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 835 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MSH5

Target: MSH5 (MutS Homolog 5 (MSH5))

Alternative Name: MSH5

Background: MSH5 is a member of the mutS family of proteins that are involved in DNA mismatch repair or meiotic recombination processes. This protein is similar to a Saccharomyces cerevisiae protein that participates in meiotic segregation fidelity and crossing-over. This protein forms heterooligomers with another member of this family, mutS homolog 4. This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair or meiotic recombination processes. This protein is similar to a Saccharomyces cerevisiae protein that participates in meiotic segregation fidelity and crossing-over. This protein forms heterooligomers with another member of this family, mutS homolog 4. Alternative splicing results in four transcript variants encoding three different isoforms.
Alias Symbols: DKFZp434C1615, G7, MGC2939, MutSH5, NG23, MUTSH5
Protein Interaction Partner: MSH4, GPS2, UBC,
Protein Size: 835

Molecular Weight: 93 kDa

Gene ID: 4439

NCBI Accession: NM_172165, NP_751897

Pathways: M Phase