PON1 antibody (C-Term)

Catalog No. ABIN2776789

The Rabbit Polyclonal anti-PON1 antibody (ABIN2776789) specifically detects PON1 in WB. The antibody is reactive with Human, Mouse, Rat, Rabbit, Cow, Horse, Dog and Guinea Pig samples.

Quick Overview for PON1 antibody (C-Term) (ABIN2776789)

Target: PON1 (Paraoxonase 1 (PON1))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Horse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PON1 Antibody

Binding Specificity: C-Term

Purpose: PON1 Antibody - C-terminal region

Sequence: ASEVLRIQNI LTEEPKVTQV YAENGTVLQG STVASVYKGK LLIGTVFHKA

Predicted Reactivity: Cow: 79%, Dog: 93%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against PON1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PON1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8107646

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PON1

Target: PON1 (Paraoxonase 1 (PON1))

Alternative Name: PON1

Background:

Background Information: PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. It is capable of hydrolyzing a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may mediate an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.

Gene Name: Paraoxonase 1

Alternative Symbols: ESA, PON, MVCD5

Protein Name: Serum paraoxonase/arylesterase 1

Molecular Weight: 39kDa

Gene ID: 5444

NCBI Accession: NP_000437

UniProt: P27169