ETS2 antibody (Middle Region)

Catalog No. ABIN2777202

Product Details anti-ETS2 Antibody

Target: ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FESFEDDCSQ SLCLNKPTMS FKDYIQERSD PVEQGKPVIP AAVLAGFTGS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against ETS2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 469 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ETS2

Target: ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

Alternative Name: ETS2 (ETS2 Products)

Synonyms: 0123/09 antibody, 0608/07 antibody, 0998/12 antibody, 3520 antibody, CG17077 antibody, CG8705 antibody, D-Ets-2 antibody, D-ets-2 antibody, DMPOINT1A antibody, Dmel\\CG17077 antibody, E(E2F)3D antibody, EK3-2 antibody, ETS2 antibody, EY3-1 antibody, Ets antibody, Ets2 antibody, Ets58AB antibody, Ets94F antibody, PNT-P1 antibody, PNTP1 antibody, PNTP2 antibody, POINT antibody, Pnt antibody, Pnt-P1 antibody, PntP1 antibody, PntP2 antibody, Pointed-P1 antibody, ets94F antibody, l(3)07825 antibody, l(3)j1B7 antibody, l(3)s118306 antibody, png antibody, pnt-P1 antibody, pnt-P2 antibody, pntP2 antibody, pntegfr antibody, pointed-RC antibody, ptd antibody, zgc:92106 antibody, wu:fe02h08 antibody, wu:fk74c05 antibody, AU022856 antibody, Ets-2 antibody, ETS2IT1 antibody, c-ets-2 antibody, pointed antibody, v-ets avian erythroblastosis virus E26 oncogene homolog 2 antibody, E26 avian leukemia oncogene 2, 3' domain antibody, ETS proto-oncogene 2, transcription factor antibody, pnt antibody, ets2 antibody, Ets2 antibody, ETS2 antibody

Background: ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma.
Alias Symbols: ETS2IT1
Protein Interaction Partner: UBC, RFWD2, TWIST1, POU5F1, TWIST2, ZFYVE9, SRA1, XPO1, TP53, SUMO2, EP300, CREBBP, NCOR1, NCOA3, SRC, ZMYND11, TDP2, STAT5B, CDK10, SMARCA4, JUN, ERG, ETS2, ETS1, NR3C1, GATA3, FOS, SPI1, BRCA1,
Protein Size: 469

Molecular Weight: 53 kDa

Gene ID: 2114

NCBI Accession: NM_001127262, NP_001120734

UniProt: P15036

Pathways: EGFR Signaling Pathway, Myometrial Relaxation and Contraction