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CDK7 antibody (N-Term)
CDK7
Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CDK7 Antibody
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Target
See all CDK7 Antibodies
CDK7
(Cyclin-Dependent Kinase 7 (CDK7))
Binding Specificity
All epitopes for CDK7 antibodies
N-Term
Reactivity
All reactivities for CDK7 antibodies
Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
Host
All hosts for CDK7 antibodies
Rabbit
Clonality
All clonalities for CDK7 antibodies
Polyclonal
Conjugate
All conjugates for CDK7 antibodies
This CDK7 antibody is un-conjugated
Application
All applications for CDK7 antibodies
Western Blotting (WB)
Sequence
VKSRAKRYEK LDFLGEGQFA TVYKARDKNT NQIVAIKKIK LGHRSEAKDG
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics
This is a rabbit polyclonal antibody against CDK7. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human CDK7
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for CDK7
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Target
CDK7
(Cyclin-Dependent Kinase 7 (CDK7))
Alternative Name
CDK7 (CDK7 Products )
Synonyms
CAK1 antibody, CDKN7 antibody, HCAK antibody, MO15 antibody, STK1 antibody, p39MO15 antibody, AI323415 antibody, AI528512 antibody, C230069N13 antibody, Cdkn7 antibody, Crk4 antibody, CD 7 antibody, CDK7 antibody, CG3319 antibody, DmCDK7 antibody, DmCdk7 antibody, DmMO15 antibody, DmMo15 antibody, Dmcdk7 antibody, Dmel\\CG3319 antibody, Mo15 antibody, cdk-7 antibody, cdk7 antibody, dCdk7 antibody, p40[MO15] antibody, p40MO15 antibody, stk1 antibody, zgc:85821 antibody, cak1 antibody, cdkn7 antibody, p39mo15 antibody, cyclin dependent kinase 7 antibody, cyclin-dependent kinase 7 antibody, Cyclin-dependent kinase 7 antibody, cyclin-dependent kinase 7 L homeolog antibody, CDK7 antibody, Cdk7 antibody, cdk7.L antibody, cdk7 antibody
Background
CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. Alias Symbols: CAK1, CDKN7, HCAK, MO15, STK1, p39MO15 Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, GTF2H4, GTF2H3, GTF2H2, GTF2H1, ERCC5, ERCC3, ERCC2, CDK7, CCNH, ATP2B4, A2M, GTF2H5, SRPK2, SRPK1, MNAT1, TP53, CDK2, CTD, MBP, CDK1, CCNB1, CCNA2, Dlg4, UVSSA, HSP90AA1, HSD17B4, HLA-DQA1, SUPT5H, POLR2A, GTF2E2, GTF2E1, CDK9, APP Protein Size: 346
Molecular Weight
39 kDa
Gene ID
1022
NCBI Accession
NM_001799 , NP_001790
UniProt
P50613
Pathways
Cell Division Cycle , DNA Damage Repair , Intracellular Steroid Hormone Receptor Signaling Pathway , Mitotic G1-G1/S Phases , M Phase
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