E2F2 antibody (Middle Region)

Catalog No. ABIN2777378

Cited in 1 publication. The Rabbit Polyclonal anti-E2F2 antibody (ABIN2777378) specifically detects E2F2 in WB. The antibody is reactive with Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig and Horse samples.

Quick Overview for E2F2 antibody (Middle Region) (ABIN2777378)

Target: E2F2 (E2F Transcription Factor 2 (E2F2))

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This E2F2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-E2F2 Antibody

Binding Specificity: Middle Region

Purpose: E2F2 Antibody - middle region

Sequence: QWVGRGMFED PTRPGKQQQL GQELKELMNT EQALDQLIQS CSLSFKHLTE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 90%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against E2F2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human E2F2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8099354

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-E2F2 antibody (ABIN2777378)

Iwata, Maruyama, Akagi, Hashikawa, Kanazawa, Tsuji, Nukina: "Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies." in: Human molecular genetics, Vol. 12, Issue 20, pp. 2625-35, (2003) (PubMed).

Target Details for E2F2

Target: E2F2 (E2F Transcription Factor 2 (E2F2))

Alternative Name: E2F2

Background:

Background Information: E2F2 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F pro

Gene Name: E2F transcription factor 2

Alternative Symbols: E2F-2

Protein Name: Transcription factor E2F2

Molecular Weight: 48kDa

Gene ID: 1870

NCBI Accession: NP_004082

UniProt: Q14209

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication