HES1 antibody (C-Term)
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- Target See all HES1 Antibodies
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HES1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AFLIPNGAFA HSGPVIPVYT SNSGTSVGPN AVSPSSGSSL TADSMWRPWR
- Predicted Reactivity
- Cow: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Hes1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Rat
- Top Product
- Discover our top product HES1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 281 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
- Alternative Name
- Hes1 (HES1 Products)
- Synonyms
- HES-1 antibody, HHL antibody, HRY antibody, bHLHb39 antibody, Hry antibody, HAIRY1 antibody, c-hairy1A antibody, Xhairy1 antibody, hairy1 antibody, hes1 antibody, Xhairy-1 antibody, Xlh1 antibody, hes family bHLH transcription factor 1 antibody, hairy and enhancer of split 1 (Drosophila) antibody, hes family bHLH transcription factor 4 antibody, hes family bHLH transcription factor 1 S homeolog antibody, hes family bHLH transcription factor 1 L homeolog antibody, HES1 antibody, Hes1 antibody, HES4 antibody, hes1.S antibody, hes1.L antibody
- Background
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Hes1 is the transcriptional repressor of genes that require a bHLH protein for their transcription. Hes1 may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Hes1 binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity.
Alias Symbols: Hes1
Protein Interaction Partner: Polr2a, Kat2b, Sfpq, Src, Crebbp, Parp1, Camk2a,
Protein Size: 281 - Molecular Weight
- 30 kDa
- Gene ID
- 29577
- NCBI Accession
- NM_024360, NP_077336
- UniProt
- Q04666
- Pathways
- DNA Damage Repair
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