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HES1 antibody (C-Term)

HES1 Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777527
  • Target See all HES1 Antibodies
    HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
    Binding Specificity
    • 16
    • 12
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 79
    • 50
    • 41
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Pig
    Host
    • 73
    • 14
    • 1
    • 1
    Rabbit
    Clonality
    • 65
    • 24
    Polyclonal
    Conjugate
    • 50
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HES1 antibody is un-conjugated
    Application
    • 70
    • 35
    • 19
    • 14
    • 14
    • 13
    • 10
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    AFLIPNGAFA HSGPVIPVYT SNSGTSVGPN AVSPSSGSSL TADSMWRPWR
    Predicted Reactivity
    Cow: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against Hes1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide corresponding to a region of Rat
    Top Product
    Discover our top product HES1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 281 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
    Alternative Name
    Hes1 (HES1 Products)
    Synonyms
    HES-1 antibody, HHL antibody, HRY antibody, bHLHb39 antibody, Hry antibody, HAIRY1 antibody, c-hairy1A antibody, Xhairy1 antibody, hairy1 antibody, hes1 antibody, Xhairy-1 antibody, Xlh1 antibody, hes family bHLH transcription factor 1 antibody, hairy and enhancer of split 1 (Drosophila) antibody, hes family bHLH transcription factor 4 antibody, hes family bHLH transcription factor 1 S homeolog antibody, hes family bHLH transcription factor 1 L homeolog antibody, HES1 antibody, Hes1 antibody, HES4 antibody, hes1.S antibody, hes1.L antibody
    Background
    Hes1 is the transcriptional repressor of genes that require a bHLH protein for their transcription. Hes1 may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Hes1 binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity.
    Alias Symbols: Hes1
    Protein Interaction Partner: Polr2a, Kat2b, Sfpq, Src, Crebbp, Parp1, Camk2a,
    Protein Size: 281
    Molecular Weight
    30 kDa
    Gene ID
    29577
    NCBI Accession
    NM_024360, NP_077336
    UniProt
    Q04666
    Pathways
    DNA Damage Repair
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