POLE3 antibody (N-Term)
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- Target See all POLE3 Antibodies
- POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Guinea Pig, Dog, Zebrafish (Danio rerio), Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLE3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MAERPEDLNL PNAVITRIIK EALPDGVNIS KEARSAISRA ASVFVLYATS
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Characteristics
- This is a rabbit polyclonal antibody against POLE3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human POLE3
- Top Product
- Discover our top product POLE3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 147 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
- Alternative Name
- POLE3 (POLE3 Products)
- Synonyms
- NCU04548.1 antibody, GB14966 antibody, zgc:73351 antibody, 1810034K18Rik antibody, YBL1 antibody, CHARAC17 antibody, CHRAC17 antibody, p17 antibody, DNA polymerase epsilon 3, accessory subunit antibody, polymerase (DNA directed), epsilon 3, accessory subunit antibody, DNA polymerase epsilon antibody, DNA polymerase epsilon p17 subunit antibody, DNA polymerase epsilon subunit 3 antibody, polymerase (DNA directed), epsilon 3 (p17 subunit) antibody, POLE3 antibody, pole3 antibody, NCU04548 antibody, CpipJ_CPIJ008666 antibody, Bm1_04865 antibody, Bm1_07285 antibody, CTRG_00708 antibody, LOAG_09571 antibody, LOC726923 antibody, Pole3 antibody
- Background
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POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Alias Symbols: p17, YBL1, CHRAC17, CHARAC17
Protein Interaction Partner: CHRAC1, DRAP1, DR1, UBC, NANS, ANXA6, gag-pol, POLE4, CPSF2, POLE, APP, YEATS2, POLE2, Cebpb, SUMO2, XRCC5, BAZ1A, SMARCA5, RAD17,
Protein Size: 147 - Molecular Weight
- 17 kDa
- Gene ID
- 54107
- NCBI Accession
- NM_017443, NP_059139
- UniProt
- Q9NRF9
- Pathways
- DNA Damage Repair
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