Endoglin antibody (N-Term)
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- Target See all Endoglin (ENG) Antibodies
- Endoglin (ENG)
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Endoglin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- ILEVHVLFLE FPTGPSQLEL TLQASKQNGT WPREVLLVLS VNSSVFLHLQ
- Predicted Reactivity
- Guinea Pig: 91%, Human: 100%, Mouse: 91%, Rat: 91%
- Characteristics
- This is a rabbit polyclonal antibody against ENG. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ENG
- Top Product
- Discover our top product ENG Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 625 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Endoglin (ENG)
- Alternative Name
- ENG (ENG Products)
- Synonyms
- ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody
- Background
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Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.
Alias Symbols: END, ORW, HHT1, ORW1, CD105
Protein Interaction Partner: ENG, TGFBR2, TGFBR1, TGFB3, TGFB1, ACVRL1, TUFM, TCTEX1D4, TGFBR3, TGFB2, INHBA, BMP7, BMP2, ACVR2A, ACVR1, ACVR2B,
Protein Size: 625 - Molecular Weight
- 68 kDa
- Gene ID
- 2022
- NCBI Accession
- NM_000118, NP_000109
- UniProt
- P17813
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