Sp3 antibody (N-Term)
-
- Target See all Sp3 Antibodies
- Sp3 (Sp3 Transcription Factor (Sp3))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Sp3 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- SSSSQLPVTI DSTGILQQNT NSLTTSSGQV HSSDLQGNYI QSPVSEETQA
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against SP3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human SP3
- Top Product
- Discover our top product Sp3 Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- Sp3 (Sp3 Transcription Factor (Sp3))
- Alternative Name
- SP3 (Sp3 Products)
- Synonyms
- SPR2 antibody, D130027J01Rik antibody, SP3 antibody, sp3 antibody, zgc:162922 antibody, Sp3 transcription factor antibody, trans-acting transcription factor 3 antibody, sp3a transcription factor antibody, Sp3 transcription factor S homeolog antibody, SP3 antibody, Sp3 antibody, sp3a antibody, sp3.S antibody
- Background
-
This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.
Protein Interaction Partner: SP1, SUMO1, PPP2R4, PPP1CC, GCH1, HLTF, TFAP4, YY1, SUMO2, UBC, RELA, MECP2, HDAC2, HDAC1, ZBTB7B, EP300, CRX, TP53, NKX3-1, CREBBP, CEBPB, ESR1, DNMT1, SFPQ, PIAS1, GRIN1, GABPA, ZBTB7A, UBE2I, STK19, RBBP4, E2F1, RB1, SP4, TNFSF10, SENP1,
Protein Size: 479 - Molecular Weight
- 52 kDa
- Gene ID
- 6670
-