CIR1 antibody (Middle Region)

Catalog No. ABIN2778094

Product Details anti-CIR1 Antibody

Target: CIR1

Binding Specificity: Middle Region

Reactivity: Human, Horse, Mouse, Pig, Cow, Rabbit, Rat, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GRNLTANDPS QEYVASEGEE DPEVEFLKSL TTKQKQKLLR KLDRLEKKKK

Predicted Reactivity: Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CIR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CIR1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CIR1

Target: CIR1

Abstract: CIR1 Products

Synonyms: CIR antibody, 1700023B02Rik antibody, 2810021A19Rik antibody, Cicr antibody, Cir antibody, 1700023b02rik antibody, RGD1309199 antibody, corepressor interacting with RBPJ, 1 antibody, CIR1 antibody, Cir1 antibody

Background: CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC). CIR is also required for RBPSUH-mediated repression of transcription.
Alias Symbols: CIR
Protein Interaction Partner: CEP76, NEK6, U2AF1, SRSF2, SRSF1, RP9, HDAC2, SAP30, SNW1, TCEA1, NCOR2, RBPJ,
Protein Size: 450

Molecular Weight: 52 kDa

Gene ID: 9541

NCBI Accession: NM_004882, NP_004873

UniProt: Q86X95