BRD2 antibody (Middle Region)

Catalog No. ABIN2778333

This Rabbit Polyclonal antibody specifically detects BRD2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig and Zebrafish (Danio rerio).

Quick Overview for BRD2 antibody (Middle Region) (ABIN2778333)

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BRD2 Antibody

Binding Specificity: Middle Region

Purpose: BRD2 Antibody - middle region

Sequence: QEQLRAVHEQ LAALSQGPIS KPKRKREKKE KKKKRKAEKH RGRAGADEDD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against BRD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BRD2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8095721

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BRD2

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Alternative Name: BRD2

Background:

Background Information: BRD2 encodes a mitogen-activated kinase which localizes to the nucleus. BRD2 maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human gene may be part of a signal transduction pathway involved in growth control.

Gene Name: Bromodomain containing 2

Alternative Symbols: FSH, NAT, RNF3, FSRG1, RING3, D6S113E, O27.1.1, BRD2-IT1

Protein Name: Bromodomain-containing protein 2

Molecular Weight: 88kDa

Gene ID: 6046

NCBI Accession: NP_005095

UniProt: P25440

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection