Cyclin D1 antibody (C-Term)

Catalog No. ABIN2778440

The Rabbit Polyclonal anti-Cyclin D1 antibody (ABIN2778440) specifically detects Cyclin D1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse and Guinea Pig samples.

Quick Overview for Cyclin D1 antibody (C-Term) (ABIN2778440)

Target: Cyclin D1 (CCND1)

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin D1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cyclin D1 Antibody

Binding Specificity: C-Term

Purpose: Ccnd1 Antibody - C-terminal region

Sequence: PDCLRACQEQ IEALLESSLR QAQQNVDPKA TEEEGEVEEE AGLACTPTDV

Predicted Reactivity: Cow: 87%, Dog: 80%, Guinea Pig: 90%, Horse: 87%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against Ccnd1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39777-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cyclin D1

Target: Cyclin D1 (CCND1)

Alternative Name: Ccnd1

Background:

Background Information: Ccnd1 is essential for the control of the cell cycle at the G1/S (start) transition.

Gene Name: Cyclin D1

Alternative Symbols: PR, cD1, Cyl-, bcl-, CycD1, Cyl-1, PRAD1, bcl-1, AI327039

Protein Name: G1/S-specific cyclin-D1

Molecular Weight: 33kDa

Gene ID: 12443

NCBI Accession: NP_031657

UniProt: P25322

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling