SIRT5 antibody (C-Term)

Catalog No. ABIN2778619

Product Details anti-SIRT5 Antibody

Target: SIRT5 (Sirtuin 5 (SIRT5))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Goat, Rabbit, Guinea Pig, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HCDLCLVVGT SSVVYPAAMF APQVAARGVP VAEFNTETTP ATNRFSHLIS

Predicted Reactivity: Cow: 86%, Dog: 93%, Goat: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SIRT5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 299 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SIRT5 antibody (ABIN2778619)

Nagarajan, Ramanathan, Dhanapriya, Dineshkumar, Subramaniyan, Gopalakrishnan: "Impact of acute kidney injury on renal allograft survival." in: Renal failure, Vol. 39, Issue 1, pp. 40-44, (2016) (PubMed).

Target Details for SIRT5

Target: SIRT5 (Sirtuin 5 (SIRT5))

Alternative Name: SIRT5 (SIRT5 Products)

Synonyms: SIR2L5 antibody, 0610012J09Rik antibody, 1500032M05Rik antibody, AV001953 antibody, zgc:92288 antibody, sirt5-a antibody, SIRT5 antibody, sir2l5 antibody, sirtuin 5 antibody, sirtuin 5 L homeolog antibody, SIRT5 antibody, Sirt5 antibody, sirt5 antibody, sirt5.L antibody, CC1G_00083 antibody

Background: SIRT5 is included in class III of the sirtuin family which ischaracterized by a sirtuin core domain. Human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
Alias Symbols: SIR2L5
Protein Interaction Partner: SIRT3, UBC, HECW2, APP, RELA,
Protein Size: 299

Molecular Weight: 33 kDa

Gene ID: 23408

NCBI Accession: NM_006800, NP_112534

UniProt: Q5T295

Pathways: SARS-CoV-2 Protein Interactome