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NXF3 antibody (C-Term)

NXF3 Reactivity: Human, Pig, Rabbit, Rat, Cow, Dog, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779117
  • Target See all NXF3 Antibodies
    NXF3 (Nuclear RNA Export Factor 3 (NXF3))
    Binding Specificity
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Pig, Rabbit, Rat, Cow, Dog, Guinea Pig, Horse
    Host
    • 19
    • 3
    Rabbit
    Clonality
    • 19
    • 3
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NXF3 antibody is un-conjugated
    Application
    • 11
    • 11
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    SSFLVDMWYQ TEWMLCFSVN GVFKEVEGQS QGSVLAFTRT FIATPGSSSS
    Predicted Reactivity
    Cow: 92%, Dog: 92%, Guinea Pig: 77%, Horse: 79%, Human: 100%, Pig: 92%, Rabbit: 92%, Rat: 77%
    Characteristics
    This is a rabbit polyclonal antibody against NXF3. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human NXF3
    Top Product
    Discover our top product NXF3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 531 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NXF3 (Nuclear RNA Export Factor 3 (NXF3))
    Alternative Name
    NXF3 (NXF3 Products)
    Synonyms
    NXF3 antibody, Gm384 antibody, RGD1564923 antibody, nuclear RNA export factor 3 antibody, NXF3 antibody, LOC523530 antibody, LOC100060140 antibody, LOC100060240 antibody, LOC785244 antibody, Nxf3 antibody
    Background
    NXF3 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF3 has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
    Protein Interaction Partner: NXT2, NXT1, SKIL, NXF1, HHV8GK18_gp81, HNRNPUL1, XPO1, NUP214,
    Protein Size: 531
    Molecular Weight
    58 kDa
    Gene ID
    56000
    NCBI Accession
    NM_022052, NP_071335
    UniProt
    Q9H4D5
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