FOXN1 antibody (N-Term)

Catalog No. ABIN2779254

The Rabbit Polyclonal anti-FOXN1 antibody is suitable to detect FOXN1 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Pig and Rabbit. It has been validated for WB.

Quick Overview for FOXN1 antibody (N-Term) (ABIN2779254)

Target: FOXN1 (Forkhead Box N1 (FOXN1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FOXN1 Antibody

Binding Specificity: N-Term

Purpose: FOXN1 Antibody - N-terminal region

Sequence: FVSDGPPERT PSLPPHSPRI ASPGPEQVQG HCPAGPGPGP FRLSPSDKYP

Predicted Reactivity: Cow: 93%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against FOXN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FOXN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100904

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FOXN1

Target: FOXN1 (Forkhead Box N1 (FOXN1))

Alternative Name: FOXN1

Background:

Background Information: Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.

Gene Name: Forkhead box N1

Alternative Symbols: WHN, RONU, TLIND, FKHL20, TIDAND

Protein Name: Forkhead box protein N1

Molecular Weight: 69kDa

Gene ID: 8456

NCBI Accession: NP_003584

UniProt: O15353