CLK4 antibody (N-Term)
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- Target See all CLK4 Antibodies
- CLK4 (CDC-Like Kinase 4 (CLK4))
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Binding Specificity
- N-Term
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Reactivity
- Mouse, Human, Dog, Guinea Pig, Rabbit, Cow, Horse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CLK4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DSDCHYLEAR CLNERDYRDR RYIDEYRNDY CEGYVPRHYH RDVESTYRIH
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against Clk4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CLK4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 481 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CLK4 (CDC-Like Kinase 4 (CLK4))
- Alternative Name
- Clk4 (CLK4 Products)
- Synonyms
- AI987988 antibody, C85119 antibody, zgc:112975 antibody, CDC like kinase 4 antibody, CDC-like kinase 4 antibody, CDC-like kinase 4b antibody, CLK4 antibody, Clk4 antibody, clk4b antibody
- Background
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Clk4 is a dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Clk4 phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Clk4 phosphorylates SRSF1 and SRSF3. Clk4 is required for the regulation of alternative splicing of MAPT/TAU. Clk4 regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
Alias Symbols: AI987988, C85119
Protein Size: 481 - Molecular Weight
- 57 kDa
- Gene ID
- 12750
- NCBI Accession
- NM_007714, NP_031740
- UniProt
- O35493
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