Choline Acetyltransferase antibody (C-Term)

Catalog No. ABIN2779369

This anti-Choline Acetyltransferase antibody is a Rabbit Polyclonal antibody detecting Choline Acetyltransferase in WB. Suitable for Human, Dog, Pig and Horse.

Quick Overview for Choline Acetyltransferase antibody (C-Term) (ABIN2779369)

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Reactivity: Human, Dog, Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Choline Acetyltransferase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Choline Acetyltransferase Antibody

Binding Specificity: C-Term

Sequence: SSFHSCKETS SSKFAKAVEE SLIDMRDLCS LLPPTESKPL ATKEKATRPS

Predicted Reactivity: Dog: 100%, Horse: 100%, Human: 100%, Pig: 91%

Characteristics: This is a rabbit polyclonal antibody against CHAT. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 630 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Choline Acetyltransferase

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Alternative Name: CHAT

Background: CHAT is an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This protein is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer disease. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
Alias Symbols: CMS1A, CMS1A2, CHOACTASE
Protein Interaction Partner: NEDD9, CAMK2A, CAMK2G, PRKCZ, PRKCG, PRKCD, PRKCE, PRKCB, PRKCA,
Protein Size: 630

Molecular Weight: 70 kDa

Gene ID: 1103

NCBI Accession: NM_020984, NP_066264

UniProt: A2BDF5

Pathways: Skeletal Muscle Fiber Development