Choline Acetyltransferase antibody
Quick Overview for Choline Acetyltransferase antibody (ABIN7266343)
Target
See all Choline Acetyltransferase (CHAT) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- CHAT Rabbit mAb
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Cross-Reactivity
- Human
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human CHAT
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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Alternative Name
- CHAT
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Background
- This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010],CHAT;CHOACTASE;CMS1A;CMS1A2;CMS6,Cell Type Marker,Cell Type Marker_Neuron marker,Neuroscience,CHAT
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Molecular Weight
- 82kDa
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Gene ID
- 1103
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UniProt
- P28329
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Pathways
- Skeletal Muscle Fiber Development
Target
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