MYCN antibody (C-Term)

Catalog No. ABIN2779428

The Rabbit Polyclonal anti-MYCN antibody (ABIN2779428) specifically detects MYCN in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Horse, Pig and Rabbit samples.

Quick Overview for MYCN antibody (C-Term) (ABIN2779428)

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYCN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYCN Antibody

Binding Specificity: C-Term

Purpose: MYCN Antibody - C-terminal region

Sequence: EDAPPQKKIK SEASPRPLKS VIPPKAKSLS PRNSDSEDSE RRRNHNILER

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 77%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against MYCN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8106092

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYCN

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Alternative Name: MYCN

Background:

Background Information: MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas

Gene Name: V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

Alternative Symbols: NMYC, ODED, MODED, N-myc, bHLHe37

Protein Name: N-myc proto-oncogene protein

Molecular Weight: 50kDa

Gene ID: 4613

NCBI Accession: NP_005369

UniProt: P04198