DBP antibody (N-Term)

Catalog No. ABIN2779501

This Rabbit Polyclonal antibody specifically detects DBP in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Horse, Sheep and Guinea Pig. It has been mentioned in 2+ publications

Quick Overview for DBP antibody (N-Term) (ABIN2779501)

Target: DBP (D Site of Albumin Promoter (Albumin D-Box) Binding Protein (DBP))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DBP Antibody

Binding Specificity: N-Term

Purpose: DBP Antibody - N-terminal region

Sequence: PKEPASCLLK EKERKAALPA ATTPGPGLET AGPADAPAGA VVGGGSPRGR

Predicted Reactivity: Cow: 85%, Dog: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 83%, Rat: 83%, Sheep: 85%

Characteristics: This is a rabbit polyclonal antibody against DBP. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DBP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32195-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-DBP antibody (ABIN2779501)

Okazaki, Matsunaga, Fujioka, Okazaki, Akagawa, Tsurudome, Ono, Kuwano, Koyanagi, Ohdo: "Circadian regulation of mTOR by the ubiquitin pathway in renal cell carcinoma." in: Cancer research, Vol. 74, Issue 2, pp. 543-51, (2014) (PubMed).

Nakabayashi, Ohta, Yamamoto, Susuki, Taguchi, Tanabe, Kondo, Hatanaka, Nagao, Tanizawa: "Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1? gene expression in pancreatic islet ?-cells." in: Biochemical and biophysical research communications, Vol. 434, Issue 2, pp. 370-5, (2013) (PubMed).

Target Details for DBP

Target: DBP (D Site of Albumin Promoter (Albumin D-Box) Binding Protein (DBP))

Alternative Name: DBP

Background:

Background Information: D-site-binding protein (DBP) is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family.

Gene Name: D site of albumin promoter (albumin D-box) binding protein

Alternative Symbols: DABP, taxREB302

Protein Name: D site-binding protein

Molecular Weight: 34kDa

Gene ID: 1628

NCBI Accession: NP_001343

UniProt: Q10586