IRF1 antibody (C-Term)

Catalog No. ABIN2779860

The Rabbit Polyclonal anti-IRF1 antibody (ABIN2779860) specifically detects IRF1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig and Sheep samples.

Quick Overview for IRF1 antibody (C-Term) (ABIN2779860)

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IRF1 Antibody

Binding Specificity: C-Term

Purpose: Irf1 Antibody - C-terminal region

Sequence: HIDGKGYLLN EPGTQLSSVY GDFSCKEEPE IDSPRGDIGI GIQHVFTEMK

Predicted Reactivity: Cow: 90%, Dog: 80%, Guinea Pig: 86%, Human: 93%, Mouse: 100%, Rabbit: 86%, Rat: 93%, Sheep: 90%

Characteristics: This is a rabbit polyclonal antibody against Irf1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36902-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IRF1

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Alternative Name: Irf1

Background:

Background Information: Irf1 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Irf1 acts as a tumor suppressor.

Gene Name: Interferon regulatory factor 1

Alternative Symbols: Irf, Irf-1, AU020929

Protein Name: Interferon regulatory factor 1

Molecular Weight: 37kDa

Gene ID: 16362

NCBI Accession: NP_032416

UniProt: P15314

Pathways: Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy