TTF1 antibody (N-Term)
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- Target See all TTF1 Antibodies
- TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))
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Binding Specificity
- N-Term
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Reactivity
- Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TTF1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RRASQTPAQE TLESEWPQKA KRKKRRREPQ TPAQETLESE WPQKAKKKKR
- Predicted Reactivity
- Mouse: 100%, Rat: 91%
- Characteristics
- This is a rabbit polyclonal antibody against Ttf1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the n terminal region of mouse Ttf1
- Top Product
- Discover our top product TTF1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 859 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))
- Alternative Name
- Ttf1 (TTF1 Products)
- Synonyms
- TTF-1 antibody, TTF-I antibody, AV245725 antibody, RGD1565673 antibody, transcription termination factor 1 antibody, transcription termination factor, RNA polymerase I antibody, TTF1 antibody, Ttf1 antibody
- Background
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Ttf1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin.Ttf1 plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription.Ttf1 interaction with BAZ2A/TIP5 recovers DNA-binding activity.
Alias Symbols: AV245725
Protein Interaction Partner: Wwtr1, Gata6,
Protein Size: 859 - Molecular Weight
- 98 kDa
- Gene ID
- 22130
- NCBI Accession
- NM_009442, NP_033468
- UniProt
- Q62187
- Pathways
- Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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