p53 antibody (Tumor Protein P53) (C-Term)

Details for Product anti-TP53 Antibody No. ABIN2779979, Supplier: Log in to see
Antigen
  • BCC7
  • LFS1
  • P53
  • TRP53
  • p53
  • Trp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • tp53
  • Xp53
  • TP53
  • tumor protein p53
  • cellular tumor antigen p53
  • transformation related protein 53
  • tumor protein p53 L homeolog
  • TP53
  • CpipJ_CPIJ002758
  • Tp53
  • tp53
  • Trp53
  • tp53.L
Alternatives
anti-Human p53 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
C-Term
170
122
84
79
71
69
66
57
55
51
48
47
47
43
41
35
33
31
25
22
22
21
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20
17
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12
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11
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4
3
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3
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3
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3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
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1
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1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
2325
503
425
182
118
93
83
83
33
22
20
19
19
16
15
13
6
4
4
4
3
3
2
2
1
1
Host
Rabbit
1331
1105
7
1
1
1
1
Clonality
Polyclonal
Conjugate
This p53 antibody is un-conjugated
82
77
64
52
46
45
45
31
31
26
25
25
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24
23
20
19
18
14
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14
14
12
7
5
5
5
5
5
5
5
5
4
3
2
2
2
Application
Western Blotting (WB)
1876
835
755
738
624
605
411
340
306
179
72
41
32
30
21
17
17
15
13
9
9
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen The immunogen is a synthetic peptide corresponding to a region of Mouse
Sequence TEEENFRKKE VLCPELPPGS AKRALPTCTS ASPPQKKKPL DGEYFTLKIR
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Sheep: 100%
Characteristics This is a rabbit polyclonal antibody against TRP53. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name TRP53 (TP53 Antibody Abstract)
Background Trp53 is a protein found in elevated levels in a great variety of transformed cells
Alias Symbols: bbl, bfy, bhy, p44, p53, Tp53
Protein Interaction Partner: PRKAA1, Rnf128, Ndn, Herc2, Rchy1, Rps26, Rpl11, Cdkn2a, Bcl2l1, Daxx, Mdm2, Wwox, Mapk8, Smyd1, Ubc, Twist1, Pten, Bard1, Ep300, Sumo1, Trp73, Trp63, Strm, Nqo1, Mif, Hspa1b, Hipk2, Axin1, Zbtb7c, Topors, Gsk3b, Foxp3, Huwe1, Park7, Ccng1, NUMB, Skil, Cu
Protein Size: 390
Molecular Weight 43 kDa
Gene ID 22059
NCBI Accession NM_011640, NP_035770
UniProt P02340
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 390 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Tumor Protein P53 (TP53) (C-Term) antibody (ABIN2779979) WB Suggested Anti-TRP53 Antibody Titration: 2.5ug/ml ELISA Titer: 1:312500 Positi...
Western Blotting (WB) image for anti-Tumor Protein P53 (TP53) (C-Term) antibody (ABIN2779979) WB Suggested Anti-TRP53 Antibody Positive Control: Lane 1: 40ug C57/B6 control mo...
Western Blotting (WB) image for anti-Tumor Protein P53 (TP53) (C-Term) antibody (ABIN2779979) WB Suggested Anti-TRP53
Antibody Titration: 2.5 µg/mL ELISA Titer: 1:.12500
Background publications Rotter, Wolf, Pravtcheva, Ruddle: "Chromosomal assignment of the murine gene encoding the transformation-related protein p53." in: Molecular and cellular biology, Vol. 4, Issue 2, pp. 383-5, 1984 (PubMed).

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