ECSIT antibody (N-Term)

Catalog No. ABIN2779983

Product Details anti-ECSIT Antibody

Target: ECSIT

Binding Specificity: N-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECSIT antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EPWLVPRPPE PQRKPIKVPA MHEDSFKPSG NRERDKASFL NAVRSFGAHN

Predicted Reactivity: Mouse: 100%

Characteristics: This is a rabbit polyclonal antibody against Ecsit. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Antigen size: 435 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ECSIT

Target: ECSIT

Alternative Name: Ecsit (ECSIT Products)

Synonyms: CG10610 antibody, DmECSIT antibody, Dmel\\CG10610 antibody, dECSIT antibody, ECSIT antibody, Sitpec antibody, SITPEC antibody, CG10610 gene product from transcript CG10610-RA antibody, ECSIT signalling integrator antibody, ecsit antibody, ECSIT signalling integrator S homeolog antibody, ECSIT antibody, CpipJ_CPIJ003637 antibody, Ecsit antibody, ecsit.S antibody

Background: Ecsit is required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase. Ecsit is an adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1.Ecsit promotes proteolytic activation of MAP3K1. Ecsit is involved in the BMP signaling pathway. Ecsit is required for normal embryonic development.
Alias Symbols: Sitpec
Protein Interaction Partner: Map3k1, Traf6, Irak1, SMURF1,
Protein Size: 435

Molecular Weight: 50 kDa

Gene ID: 26940

NCBI Accession: NM_012029, NP_036159

UniProt: Q9QZH6

Pathways: TLR Signaling, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome