Progesterone Receptor antibody (N-Term)
-
- Target See all Progesterone Receptor (PGR) Antibodies
- Progesterone Receptor (PGR)
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Progesterone Receptor antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- TELKAKGPRA PHVAGGPPSP EVGSPLLCRP AAGPFPGSQT SDTLPEVSAI
- Predicted Reactivity
- Human: 100%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against PGR. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PGR
- Top Product
- Discover our top product PGR Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 933 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- Progesterone Receptor (PGR)
- Alternative Name
- PGR (PGR Products)
- Synonyms
- NR3C3 antibody, PR antibody, 9930019P03Rik antibody, BB114106 antibody, ENSMUSG00000074510 antibody, PR-A antibody, PR-B antibody, XPR-1 antibody, pgr antibody, xpr-2 antibody, LOC443444 antibody, PGR antibody, pg antibody, pr antibody, gb:dq017620 antibody, progesterone receptor antibody, progesterone receptor L homeolog antibody, PGR antibody, Pgr antibody, pgr.L antibody, pgr antibody
- Background
-
This protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NR3C3, PR
Protein Interaction Partner: BCAS2, SRC, PGR, Dlg4, PARP1, ANP32A, XRCC5, PRKDC, XRCC6, MAGEA11, FKBP5, RBM23, RBM39, KAT2B, BRCA1, STUB1, DNAJC7, PPP5C, FKBP4, BPTF, CDK2, COPS5, NCOA1, UBC, ESR1, NCOA2, CCNA1, NCOA3, STAT3, SP1, Jdp2, Batf3, STAT5B, STAT5A, FGFR2, PRDM2, NCOR2, TAF
Protein Size: 933 - Molecular Weight
- 99 kDa
- Gene ID
- 5241
- NCBI Accession
- NM_000926, NP_000917
- UniProt
- P06401
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
-