HMGA1 antibody (N-Term)
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- Target See all HMGA1 Antibodies
- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Guinea Pig, Zebrafish (Danio rerio), Goat, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HMGA1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPKEPSEV PTPKRPRGRP
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against HMGA1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HMGA1
- Top Product
- Discover our top product HMGA1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 96 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
- Alternative Name
- HMGA1 (HMGA1 Products)
- Synonyms
- HMG-R antibody, HMGA1A antibody, HMGIY antibody, Hmgi antibody, Hmgiy antibody, hmga1 antibody, hmgiy antibody, wu:fb12b06 antibody, wu:fb18f11 antibody, wu:fc19f01 antibody, wu:fi38b05 antibody, zgc:85677 antibody, AL023995 antibody, Hmga1a antibody, Hmga1b antibody, Hmgy antibody, HMG-I(Y) antibody, HMG-Y antibody, HMGA1 antibody, zgc:153948 antibody, high mobility group AT-hook 1 antibody, high mobility group protein HMG-I/HMG-Y antibody, high mobility group AT-hook 1a antibody, high mobility group AT-hook 1b antibody, HMGA1 antibody, Hmga1 antibody, TSC_c24220 antibody, hmga1a antibody, LOC705105 antibody, hmga1b antibody
- Background
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This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: HMG-R, HMGA1A, HMGIY, MGC12816, MGC4242, MGC4854
Protein Interaction Partner: NCOR2, UBE2I, PPARG, UBC, UPF2, HTT, OLA1, DNAJC8, PSIP1, METAP2, SYNCRIP, CWC27, HNRNPDL, EIF2S2, PCBP2, PCBP1, PA2G4, NPM1, NCL, HSPA1A, HNRNPL, HNRNPD, HNRNPAB, HNRNPA1, HMGB3, HMGB2, HMGB1, GTF2F2, XRCC6, CSNK2A1, RCC1, CDK1, APEX1, ANXA2, ANXA1, SSB,
Protein Size: 96 - Molecular Weight
- 11 kDa
- Gene ID
- 3159
- NCBI Accession
- NM_002131, NP_002122
- UniProt
- Q5T6U8
- Pathways
- Nuclear Hormone Receptor Binding, Autophagy
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